Our Lab News
We had a great time at the 2023 Orthopaedic Research Society Annual Meeting in Dallas, TX! 🌆
We presented some of our works at 2023 Orthopaedic Research Society Annual Meeting in Dallas, TX: Bioelectricity in Medicine Drug Delivery using Charged Biomaterials - Ambika (Spotlight Talk) Cationic Peptide Modified Exosomes for Cartilage Targeting for Applications...
Our recent work about intra-articular kinetics of multi-arm Avidin is now published in Osteoarthritis and Cartilage📄
Congrats to Tengfei for his last Ph.D. work in our lab published in Osteoarthritis and Cartilage: Intra-articular kinetics of a cartilage targeting cationic PEGylated protein for applications in drug delivery. This paper is now available online [HERE]
Happy to announce that the Biophysical Journal recently published a new and notable editorial highlighting our work on effects of cationic carriers on cartilage mechanics!📄
Our work previously on the effect of polycationic peptide carriers on cartilage electromechanical properties was highlighted in the "New and Notable" section of Biophysical Journal. Read it [HERE]
Our latest publication in Acta Biomaterialia developing cationic peptide carriers for cartilage targeting📄
This is our latest work on cationic peptide carriers (CPC) for cartilage targeting in drug delivery for osteoarthritis. We found significant competing interactions between CPC with synovial fluid constituents before uptake in cartilage and investigated the in vivo...
Application of cationic peptides in drug delivery published in Arthritis Research Therapy📄
Congrats to Armin, Bill, and Tengfei for their recent publication in Arthritis Research Therapy! Armin led this work in demonstrating that cationic peptide-conjugated IGF is more effective in suppressing OA-associated catabolism than unmodified IGF. This is the first...
Effects of polycationic drug carriers on the electromechanical and swelling properties of cartilage published in Biophysical Journal📄
Congratulations to Matt, Armin, and Sanjana on this paper published by Biophysical Journal! We demonstrated that charge-based drug delivery using polycationic peptide affects the electromechanical properties of cartilage. You can read the paper [HERE]
Prof. Bajpayee receives the 2022 Soren Buus Outstanding Research Award!🏅
Prof. Bajpayee receives the 2022 Soren Buus Outstanding Research Award! This Award recognizes and rewards an outstanding researcher for accomplishments in advancing the frontiers of knowledge. The awardees illustrate the important role that research plays in...
Our latest publication in Cartilage using multi-arm avidin to mediate sustained delivery of Kartogenin📄
Congratulations to Tengfei, Irfhan, and Armin on their latest publications in Cartilage! In this paper, we designed cartilage targeting and homing formulations for the delivery of a pro-anabolic OA drug, KGN by using a branched cationic protein-based carrier,...
