In this work led by Dr. Tanvi Pathrikar, we engineered naturally secreted exosomes by reversing their surface charge to enable cartilage-targeting properties via electrostatic interactions. This drug delivery system enabled a sustained interleukin-1 receptor antagonist (IL-1RA) delivery into cartilage for OA therapy. The paper is online and can be accessed [HERE]!
Congrats to Tanvi Pathrikar and Coauthors on the recently published work on cartilage-targeting exosomes for OA therapy in Osteoarthritis and Cartilage
