by BajpayeeLab | Apr 21, 2025 | Publication
In collaboration with Dr. Ryan Porter at UAMS, Timothy Boyer and Co-Authors evaluated the kinetics, stability, and immunogenicity of Cationic Peptide Carriers (CPCs) after a single intra-articular injection using a rabbit knee injury model. Our key findings: CPCs...
by BajpayeeLab | Apr 15, 2025 | Publication
Our recently published paper, which was spearheaded by Dr. Tanvi Pathrikar, was highlighted by Dr. Chris Evans on the latest Osteoarthritis and Cartilage (OAC) editorial. In this work, we introduced cationic exosome as a promising non-viral carrier for OA therapeutic...
by BajpayeeLab | Mar 31, 2025 | Publication
In this work led by Dr. Tanvi Pathrikar, we engineered naturally secreted exosomes by reversing their surface charge to enable cartilage-targeting properties via electrostatic interactions. This drug delivery system enabled a sustained interleukin-1 receptor...
by BajpayeeLab | Oct 8, 2024 | Publication
We highlight the promise exosomes have as a next-generation therapy for OA and recent advances in engineering exosomes to enhance their targeted therapeutic potential. The paper is published in Nanoscale and can be accessed [HERE]!
by BajpayeeLab | Apr 13, 2024 | Publication
This work demonstrated that surface-modified cationic exosomes can penetrate through the full thickness of early-stage arthritic cartilage and deliver the encapsulated genetic materials to chondrocytes residing in the tissue’s deep layers for OA treatment. The paper...
