The Bajpayee Lab @ Northeastern

Tanvi and Tim won the prize for poster categories at the College of Engineering Expo. Congrats!

Our recently published article explores the use of combining IL-1Ra with cationic drug delivery carriers for post-traumatic osteoarthritis. The work demonstrates that electrically charged IL-1Ra is more effective than neutral IL-1Ra in repairing cartilage. It...

We presented some of our works at 2023 Orthopaedic Research Society Annual Meeting in Dallas, TX: Bioelectricity in Medicine Drug Delivery using Charged Biomaterials - Ambika (Spotlight Talk) Cationic Peptide Modified Exosomes for Cartilage Targeting for Applications...

Congrats to Tengfei for his last Ph.D. work in our lab published in Osteoarthritis and Cartilage: Intra-articular kinetics of a cartilage targeting cationic PEGylated protein for applications in drug delivery. This paper is now available online [HERE]

Our work previously on the effect of polycationic peptide carriers on cartilage electromechanical properties was highlighted in the "New and Notable" section of Biophysical Journal. Read it [HERE]

This is our latest work on cationic peptide carriers (CPC) for cartilage targeting in drug delivery for osteoarthritis. We found significant competing interactions between CPC with synovial fluid constituents before uptake in cartilage and investigated the in vivo...

Congrats to Armin, Bill, and Tengfei for their recent publication in Arthritis Research Therapy! Armin led this work in demonstrating that cationic peptide-conjugated IGF is more effective in suppressing OA-associated catabolism than unmodified IGF. This is the first...

Congratulations to Matt, Armin, and Sanjana on this paper published by Biophysical Journal! We demonstrated that charge-based drug delivery using polycationic peptide affects the electromechanical properties of cartilage. You can read the paper [HERE]

Prof. Bajpayee receives the 2022 Soren Buus Outstanding Research Award! This Award recognizes and rewards an outstanding researcher for accomplishments in advancing the frontiers of knowledge. The awardees illustrate the important role that research plays in...